Priapism is a rare but potentially serious side effect associated with medications like Filitra, which contains vardenafil as its active ingredient. Priapism is a prolonged and painful erection that lasts for more than four hours and is not related to sexual arousal or stimulation. This condition can be a medical emergency because if left untreated, it can lead to damage to the penile tissue and permanent erectile dysfunction. The risk of priapism with medications like Filitra is due to their mechanism of action. Vardenafil, like other PDE5 inhibitors (phosphodiesterase type 5 inhibitors), works by increasing blood flow to the penis, which helps men with erectile dysfunction achieve and maintain an erection when sexually stimulated. However, in rare cases, this increased blood flow can lead to a persistent erection. Taking more than the prescribed or recommended dosage of Filitra can increase the risk of priapism.Certain medical conditions, such as sickle cell anemia, leukemia, and multiple myeloma, are associated with a higher risk of priapism when using PDE5 inhibitors. Interactions with other medications, such as anticoagulants and alpha-blockers, can potentially increase the risk of priapism.It’s important to use Filitra or any medication containing vardenafil as directed by a healthcare professional and not to exceed the recommended dosage. If you experience an erection that lasts more than four hours while using Filitra, seek immediate medical attention, as priapism requires prompt treatment to prevent potential complications. Your healthcare provider can help you understand the risks and benefits of using Filitra or other PDE5 inhibitors and can provide guidance on the safe and appropriate use of these medications
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